ResultsĮighty-seven male and 63 female patients (613 levels total) underwent IPLF in which V-CBA was implanted. Lenke scale C or D were categorized as pseudarthrosis. The primary composite endpoint of fusion status was dependent upon two main criteria: bridging bone per the Lenke scale (classified as “A” definitely solid or “B” possibly solid) and posterior hardware status (intact). De-identified images were assessed radiologically. Standing anteroposterior (AP) and lateral images were collected prior to surgery and again at the terminal visit, which took place between 6 and 33 months post-operatively. Patient diagnoses included degenerative disc disease, spondylosis, spondylolisthesis, or spondylolysis with or without stenosis. V-CBA was mixed with local autograft bone. All surgeries were performed by one surgeon. Retrospective data were collected from 150 consecutive patients who had undergone IPLF surgery between January 1, 2015, and March 31, 2018, in which V-CBA was used. The purpose of this retrospective study was to evaluate efficacy and safety of one CBA (V-CBA) in patients who underwent instrumented posterolateral fusion (IPLF). Surgery may include the use of fusion-enhancing implants, such as cellular bone allografts (CBAs). Fusion surgery may be indicated when non-operative treatments have failed to provide relief. Low back pain (LBP) is the leading cause of absence from work, disability, and impaired quality of life.
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